This course is based on the fundamental aspects of the inorganic and organic chemistry courses, covers the fundamentals of synthetic design and strategy in organic synthesis. At the same time, let the students to learn the related mechanistic aspects (chemo, regio, stereoselectivity); and let them know better how to design their own experiments; to understand and apply knowledge of organic reactions and synthetic strategy toward wide applications in the context of the synthesis of therapeutic drugs, natural products, and advanced materials.