生物大分子结构与功能

(李婉秋)MED50262024秋 2023秋 2022秋  
2024秋 2023秋 2022秋
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选课类别:专业任务 教学语言:英文
课程类别:专业选修课 开课单位:药理学系
课程层次:未知 获得学分:3.0
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课程简介(教工部数据)
生命是复杂且动态的。所有的生物都是由同一组化学元素组成的,主要是碳、氮、氧、氢、硫和磷。生物大分子包含核酸、蛋白质和多糖,它们分别由核苷酸、氨基酸和单糖形成。生物大分子通过与其他生物大分子或者小分子相互作用而发挥其生物学功能,也是正常生命活动的基础。研究和学习生物大分子的结构,有利于了解其作用机制,也是理解正常生命活动、探讨疾病发生和发展分子机制的重要手段。本课程的目标是通过讲授生物大分子的结构与功能之间的相关性,帮助学生掌握生物大分子的基本组成,理解生物大分子发挥作用的结构基础,了解生物大分子研究相关的常用技术手段,同时,学生通过学习本课程,为后续的深造学习和实际的科学研究奠定重要基础。


Life is complex and dynamic. All organismsare composed of the same set of chemical elements, primarily carbon, nitrogen,oxygen, hydrogen, sulfur, and phosphorus. Certain biomolecules become linked toform polymers called biomacromolecules. Examples include nucleic acids,proteins and polysaccharides, which are formed from nucleotides, amino acidsand sugars, respectively. Biomacromolecules play crucial biological rolesthrough interacting with other macromolecules or small molecules, which is alsothe basis of normal living processes. Studying the structure ofbiomacromolecules is helpful to understand their functions. It is also animportant means to understand normal living processes and explore the molecularmechanism of disease occurrence and development. This course aims to introduce thestructure characteristics and structure-function relationships of biomacromolecules,that helps students to memorize biomacromolecules’ basic elements, understandthe structure basis of a functional biomacromolecule, an overview of living processesat molecular level. With this course, students will have a knowledge of techniquesused in the structural and functional research of biomacromolecules as well. 
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