This course starts fromthe introduction of Advanced Design-Manufacture Integrated Technique, coveringengineering background and state-of-the-art, from simulation to digital twin, fromexperimental design to big data, from surrogate modelling to artificialintelligence, etc., and then give practical engineering cases with a betterclarification of the use of relevant fundamental knowledge and technique,guiding students to well master and apply Advanced Design-ManufactureIntegrated Technique for solving practical engineering problems.