干细胞与再生生物学

(余化鹏)BIO3322024春 2023春  
2024春 2023春
8.0(1人评价)
  • 课程难度
    中等
  • 作业多少
    很少
  • 给分好坏
    超好
  • 收获大小
    很多
选课类别:专业任务 教学语言:双语
课程类别:专业选修课 开课单位:生物系
课程层次:本科 获得学分:2.0
课程主页:暂无(如果你知道,请点右上角“编辑课程信息”添加!)
课程简介(教工部数据)
该课程介绍组织器官损伤后再生的过程,通过比较不同器官,不同物种再生能力的差别,引导学生分析归纳出再生的基本特征。围绕需要再生医学手段治疗的重大疾病,包括:心血管疾病、自身免疫性疾病、糖尿病、阿尔兹海默病、帕金森病等展开教学,主要讲授基于干细胞和发育路径的研究思路和成果,并介绍组织工程,器官移植等领域的最新进展。


In this course, we will explore basic mechanisms of how cells differentiate into specific tissues in response to a variety of biologic signalling molecules. We will discuss the use of such factors for in vitro tissue production. For example, bone morphogenetic proteins can be used in vitro to drive the differentiation of adult stem cells towards bone and heart. We will also study the cellular mechanisms involved in the cloning of animals and how Scottish researchers produced the sheep Dolly using the nucleus of a mammary gland cell from an adult sheep. We will read papers describing organ production, such as the in vitro formation of beating heart cells. We will discuss how studies of the developmental, cellular and molecular biology of regeneration have led to the discovery of new drugs.
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