肿瘤生物学原理与进展

(董金堂, 张宝童)MED50412023春  
2023春
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选课类别:专业任务 教学语言:英文
课程类别:专业必修课 开课单位:医学院
课程层次:研究生 获得学分:3.0
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课程简介(教工部数据)
        《肿瘤生物学原理与进展》是基于多个原因开设的,包括癌症研究是生命科学和基础医学的重大研究领域,恶性肿瘤是中国疾病致死的第一大原因,抗肿瘤药物所属的生物医药产业是深圳市七大战略性未来产业之一等。该课程围绕癌生物学各主要方向如细胞增殖与分化、细胞生存与死亡、DNA损伤反应与基因组不稳定性、细胞浸润与肿瘤转移、肿瘤微环境与肿瘤演进、肿瘤代谢与治疗、肿瘤免疫逃逸、肿瘤预防与诊断治疗等共21个题目。每个题目占用两节课。第一节课由授课教师讲授一个题目的基本概念和原理。第二节课则由授课教师指导、学生介绍并讨论与当天讲授题目相关、属于该领域重要进展的学术论文。第二节课一方面加强学生对相关概念和原理的理解,另一方面使学生获得对相关领域研究进展的了解与思考。还将安排2-3次学术报告,由处于所选研究领域国际前沿的一线科学家介绍其研究进展。通过该课程的学习,将掌握癌生物学各个主要方向的基本概念和原理,了解相关研究进展,同时获得研究思维和研究思路方面的训练。


        The course“Cancer Biology Principles and Advances” is based on the following rationales:cancer research is a major area of biological and medical sciences, malignanttumors constitute the first cause of disease-induced deaths in China, and thebiomedical industry, including anticancer drugs development, is one of theseven strategic future industries in Shenzhen. This course covers 21 topics inall major areas of cancer biology, including cell proliferation anddifferentiation, cell survival and death, DNA damage response and genomicinstability, cell invasion and tumor metastasis, tumor microenvironment andtumor progression, tumor metabolism and therapies, tumor immune evasion, andtumor prevention and tumor diagnosis and treatment, etc. Each topic takes twoclasses. In the first class, the lecturer will teach related concepts andprinciples. In the second class, the lecturer will guide the students topresent and discuss research papers representing critical advances in thatday’s topic. The second class not only strengthens a student’s understanding ofconcepts and principles but also helps a student learn and think about advancesin a research area. The course will also include 2-3 research seminars, eachpresented by a first-line scientist in a field and covering the presenter’sup-to-date research. After this course’s study, one will master the basicconcepts and principles in all major areas of cancer biology, understandresearch advances in these areas, and receive training in research thinking andideas.
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董金堂

人类细胞生物和遗传学系

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张宝童

人类细胞生物和遗传学系

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