RNA生物学及疗法

As the key component of the central dogma, ribonucleic acid (RNA) is a special type of molecule. RNA may function as information molecule to store and decode the genetic information, and also can perform a wide range of biological functions by participating in different reactions.  The research on the new function of RNA has been the forefront of molecular biology and biotechnology in recent years. In this course, I will focus on the life cycle of RNA to introduce the basic principles of RNA biology, including the transcription, modification, processing, transposition, translation and degradation of different types of RNAs.  I will also discuss the new technologies in RNA research and the potential application of different RNAs as new drug modality. The course will expose the student to the emerging RNA therapy and technology, providing an introduction on both the medical applications and their underlying logic.