Lecture, 4 credits, 4 hours per week. Pre-requisites: None. This course provides an intuitive understanding of basic mathematical knowledge for the students of Biomedical Science (Joint Educational Programme) .It focuses on the bases of the function, differentiation, integration and their principles, and theorems are explained. Specially, the calculus of on variable or several variables are introduced by many examples of their applications. It is significant that this course can help students to combine clinical medicine, practical pharmacy, and real-world biology with mathematics by problem-solving approaches, concise logical deduction style, and comprehensive applications.