线粒体生物学

Mitochondrial biomedical research is currently a hot topic in the field of biomedical research. Since the 1990s, the central position of mitochondria in cell apoptosis has been revealed. In addition to serving as an "energy factory," mitochondria have been endowed with a new role as a hub for cellular signal regulation.As a signal transduction hub of cells, mitochondria play an important role in processes such as cell survival and death, maintenance of intracellular ion homeostasis, regulation of cellular redox homeostasis, and control of cellular metabolic levels. In addition, mitochondria are a common source of many complex diseases. However, due to the unique structure of mitochondria, the complexity of their internal environment, and the diversity of mitochondrial functions, it is currently unclear how mitochondria regulate their own homeostasis, regulate various functional activities of cells and the body, and many other issues. Therefore, the field of mitochondrial research is currently the most dynamic and important direction in basic biology, biomedical, translational and clinical research, nurturing new significant discoveries.This course will delve into the structure, function, and role of mitochondria in health and disease. By providing a comprehensive introduction to mitochondrial anatomy, research history, and its association with energy metabolism, cell death, diseases, and other aspects, students will gain a deeper understanding of the importance and impact of mitochondria. Through the study of this course, students will gain a deep understanding of the basic concepts of mitochondrial biomedical field, as well as its importance in life activities and its role in disease occurrence and development, laying a solid foundation for future scientific research and clinical practice.