分子流行病学与因果推断

(赵健)MED50642024秋  
2024秋
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选课类别:专业任务 教学语言:中文
课程类别:专业选修课 开课单位:公共卫生及应急管理学院
课程层次:未知 获得学分:2.0
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课程简介(教工部数据)
《分子流行病学与因果推断》是一门专注于探索分子生物学与流行病学交叉领域的课程。在这门课程中,学生将学习如何利用现代分子生物学的技术和方法来理解疾病的发生、传播和预防,以及如何从多维度数据中探索疾病的成因和影响因素。课程内容通常包括以下几个方面:基础分子生物学知识:学习DNA、RNA、蛋白质等分子生物学基本概念和技术,以及它们在疾病研究中的应用。研究设计:介绍分子流行病学中使用的不同研究设计,如队列研究、病例对照研究和实验设计,并了解它们的优缺点。因果推断方法:学习各种因果推断方法,如倾向得分匹配、工具变量分析和有向无环图,并了解如何将这些方法应用于流行病学研究中。疾病研究案例:通过具体的疾病案例,如癌症、心血管疾病、传染病等,来展示分子流行病学和因果推断方法的应用。这门课程旨在培养学生综合运用分子生物学、流行病学和因果推断方法来解决健康问题的能力,为他们未来在公共卫生、医学研究、药物开发等领域的工作打下坚实的基础。


Molecular Epidemiology and Causal Inference is a course dedicated to exploring the intersection of molecular biology and epidemiology. In this course, students will learn how to utilize modern molecular biology techniques and methods to understand the occurrence, transmission, and prevention of diseases, as well as to explore the causes and influencing factors of diseases from multidimensional data.The course typically covers the following aspects:Fundamental Molecular Biology Knowledge: Students will learn basic concepts and techniques of molecular biology, such as DNA, RNA, proteins, and their applications in disease research.Research Design: Introduction to various research designs used in molecular epidemiology, such as cohort studies, case-control studies, and experimental designs, and understanding their strengths and weaknesses.Causal Inference Methods: Learning various causal inference methods, such as propensity score matching, instrumental variable analysis, and directed acyclic graphs, and understanding how to apply these methods in epidemiological research.Disease Research Cases: Through specific disease cases, such as cancer, cardiovascular diseases, infectious diseases, etc., the application of molecular epidemiology and causal inference methods will be demonstrated.The course aims to cultivate students' ability to comprehensively apply molecular biology, epidemiology, and causal inference methods to solve health problems, laying a solid foundation for their future work in public health, medical research, drug development, and other fields.
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