This course is designed to deepen students' comprehensive understanding of the field of translational medicine, with a particular focus on developing key skills and knowledge for the translation of biomedical research outcomes into clinical applications. The course content will concentrate on the core areas of translational medicine, including team collaboration and innovation commercialization under the "industry-academia-research-medicine" model, as well as advancements in key clinical research areas such as liver transplantation, neurosurgery, respiratory diseases, HPV-related tumor translational strategies, and emerging developments in critical care medicine and phage therapy. Additionally, the course will explore vaccine development, antiviral drug design, and the modern research and development and translation pathways for drugs and medical devices, aiming to cultivate students' comprehensive abilities from basic research to clinical application. Through engagement in case analyses, project practice, and hands-on operations, students will gain valuable practical experience and enhance their critical thinking and problem-solving skills. The study of this course will not only lay a solid foundation of theoretical and practical knowledge for students' future professional development in biomedical research, drug development, and clinical trial design but also inspire their passion for translational medicine, preparing them well for future careers and scientific innovations.