？In recent 20 years, QC has made significant progresses and expects to break through in next 15 years. Among several options, Silicon-based approach is among the most promising ones. This course focuses on basic concepts and introduction of QC, device realization of QC, advantages of Silicon based devices, device modeling in cryogenic temperature (4.2K and below), current research foci and future trend, as well as parallel comparison between the historical milestones of mainstream CMOS technology development and QC path and the empowering of the former to the later.