In the traditional molecular biology experiment and bioinformatics, the acquisition of genome sequence information and gene sequencing instrument is the most important link and bridge. This course focuses on cultivating students' scientific research literacy. Students will explore what is a foundation in a unique application scenario from different perspectives such as biology, genomics and bioinformatics, and the relationship between genes and human health. They will design scientific research projects independently, and finally reveal the relationship between human characteristics and genes through hands-on experiments. The course consists of five units: “Introduction to Application Scenes”, “Independent Design Scientific Research Project”, “Wet Experiment”, “Dry Experiment” and “Scientific Practice”. Students can understand the cutting-edge knowledge of genomics and gene technology in a simple way, and complete molecular biology experiments and bioinformatics analysis.